Publications

  • Zhang K, Zheludev IN, Hagey RJ, Haslecker R, Hou YJ, Kretsch R, et al. Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome. Nat Struct Mol Biol. 2021 Sep;28(9):747–54.

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  • Wu MT-P, D’Souza V. Alternate RNA Structures. Cold Spring Harb Perspect Biol. 2020 Jan;12(1):a032425.

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  • Pham VV, Salguero C, Khan SN, Meagher JL, Brown WC, Humbert N, et al. HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry. Nat Commun. 2018 Oct 15;9:4266.

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  • Longhini AP, LeBlanc RM, Becette O, Salguero C, Wunderlich CH, Johnson BA, et al. Chemo-enzymatic synthesis of site-specific isotopically labeled nucleotides for use in NMR resonance assignment, dynamics and structural characterizations. Nucleic Acids Res. 2016 Apr 7;44(6):e52.

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  • Imai S, Kumar P, Hellen CUT, D’Souza VM, Wagner G. An accurately pre-organized IRES RNA structure enables eIF4G capture for initiating viral translation. Nat Struct Mol Biol. 2016 Sep;23(9):859–64.

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  • Miller SB, Yildiz FZ, Lo JA, Wang B, D’Souza VM. A structure-based mechanism for tRNA and retroviral RNA remodelling during primer annealing. Nature. 2014 Nov;515(7528):591–5.

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  • Johnson SF, Collins JT, D’Souza VM, Telesnitsky A. Determinants of Moloney Murine Leukemia Virus Gag-Pol and Genomic RNA Proportions. J Virol. 2014 Jul;88(13):7267–75.

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  • Alvarado LJ, LeBlanc RM, Longhini AP, Keane SC, Jain N, Yildiz ZF, et al. Regio-selective Chemical-Enzymatic Synthesis of Pyrimidine Nucleotides Facilitates RNA Structure and Dynamics Studies. Chembiochem. 2014 Jul 21;15(11):1573–7.

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  • Durney MA, D’Souza VM. HIV-1: Packaging a Shifty Genome? Cell Host & Microbe. 2013 Feb 13;13(2):123–5.

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  • Houck-Loomis B, Durney MA, Salguero C, Shankar N, Nagle JM, Goff SP, et al. An equilibrium-dependent retroviral mRNA switch regulates translational recoding. Nature. 2011 Nov 27;480(7378):561–4.

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  • Miyazaki Y, Irobalieva RN, Tolbert B, Smalls-Mantey A, Iyalla K, Loeliger K, et al. Structure of a Conserved Retroviral RNA Packaging Element by NMR Spectroscopy and Cryo-Electron Tomography. J Mol Biol. 2010 Dec 17;404(5):751–72.

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  • Durney MA, D’Souza VM. Preformed Protein-binding Motifs in 7SK snRNA: Structural and Thermodynamic Comparisons with Retroviral TAR. Journal of Molecular Biology. 2010 Dec 10;404(4):555–67.

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  • D’Souza V, Summers MF. How retroviruses select their genomes. Nat Rev Microbiol. 2005 Aug;3(8):643–55.

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  • D’Souza V, Summers MF. Structural basis for packaging the dimeric genome of Moloney murine leukaemia virus. Nature. 2004 Sep;431(7008):586–90.

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  • D’Souza V, Dey A, Habib D, Summers MF. NMR Structure of the 101-nucleotide Core Encapsidation Signal of the Moloney Murine Leukemia Virus. Journal of Molecular Biology. 2004 Mar 19;337(2):427–42.

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  • D’Souza V, Melamed J, Habib D, Pullen K, Wallace K, Summers MF. Identification of a high affinity nucleocapsid protein binding element within the moloney murine leukemia virus Ψ-RNA packaging signal: implications for genome recognition1 1Edited by I. Tinoco. Journal of Molecular Biology. 2001 Nov 23;314(2):217–32.

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